1.0 OBJECTIVE:
To lay down a standard procedure for Silica Gel Activation.
2.0 SCOPE:
This SOP is applicable for Silica Gel Activation in Quality Control Laboratory
3.0 RESPONSIBILITY:
Officers / Executive – Quality Control shall be responsible for follow that procedure.
4.0 ACCOUNTABILITY:
Head QC and Head QA shall be accountable for compliance of this SOP.
5.0 ATTACHMENTS:
Silica Gel Replacement and destruction Record Attachment-I
Label for Silica gel Replacement Attachment-II
6.0 PROCEDURE:
6.1 Ensure that color of silica gel shall be changed from blue to Pink color before activation of silica gel.
6.2 Collect the silica gel from different area of laboratory, which shall under activation.
6.3 Switch on oven and set the temperature 105°C.
6.4 Keep silica gel in tray and put in oven after achieving 105° C, for six hours then check the color of silica gel.
6.5 If the color of silica gel color changed from pink to blue it means silica gel become activated.
6.6 If the color of silica gel not changed from pink to blue color than continue the process till color changed.
6.7 After activation of silica gel, remove from oven and cool at room temperature and store for further use in laboratory as per the requirement.
6.8 Label stating the details of silica gel filling shall be paste on the desiccators or container, where silica gel is used as desiccant.
6.9 If silica doesn’t get activated even after heating then discard the used silica gel and record the detail of destruction in attachment-I and then replace the silica with new stock.
6.10 Frequency of activation of silica gel: after 15 days
7.0 REFERENCES:
In-house
8.0 ABBREVIATIONS:
SOP: Standard Operating Procedure
QC: Quality Control
QA: Quality Assurance
°C: Degree centigrade
9.0 DISTRIBUTION LIST:
Quality Assurance Department
Quality Control Department
10. 0HISTORY OF REVISION:
| Version Number | Effective Date | Reason for Revision |
Silica Gel Replacement and destruction Record Attachment-I
| S. No. | Date of Filling | Name of Equipment | Equipment ID | Activation Date | Next due Date
of Filling |
Destruction Date | Filled by | Checked By |
Label for Silica gel Replacement Attachment-II
| Date of silica gel Filling:
Due date of Activation: Next due date of Activation:
|
| Filled by: Verified by: |
| Format No. |
